It presents major topics of immunology through a selection of clinical cases that reinforce and extend the basic science. Each case history is preceded by essential scientific facts about the immunological mechanisms o. This new edition vividly illustrates the importance of an understanding of immunology in diagnosis and therapy.
Seven completely new cases have been added to this edition. Each case is presented in a consistent format. Basic scientific facts introduce the case history, providing essential background information. The case history is followed by a summary of the disease under study.
Cases end with several questions and discussion points that highlight lessons learned from the case. His family history revealed that he had inherited this defect in antibody synthesis as an X-linked recessive abnormality. Pyogenic bacteria are the major cause of infection in X-linked agammaglobulinemia. It includes cases that illustrate both recently discovered genetic immunodeficiencies and some more familiar and common diseases with interesting immunology.
It is helpful for medical and pre-medical students. As well as being a valuable review aid, Case Studies in Immunology introduces in a clinical setting the major common disorders of immunity, including hypersensitivity types I-IV and autoimmune disorders such as lupus and multiple sclerosis.
It also describes and explains the consequences of some of the most important immune deficiencies. Each case history is preceded by basic scientific facts essential to understanding the immunology behind the disease or disorder. X-linked Lymphoproliferative Syndrome Hemophagocytic Lymphohistiocytosis Chediak-Higashi Syndrome Wiskott-Aldrich Syndrome Hyper IgE Syndrome Ataxia Telangiectasia X-linked Hypohidrotic Ectodermal Dysplasia and Immunodeficiency Interferon- Receptor Deficiency Severe Congenital Neutropenia Chronic Granulomatous Disease Leukocyte Adhesion Deficiency Recurrent Herpes Simplex Encephalitis Interleukin 1 Receptor-Associated Kinase 4 Deficiency Congenital Asplenia Hereditary Angioedema Deficiency of the C8 Complement Component Hereditary Periodic Fever Syndromes Systemic Juvenile Idiopathic Arthritis Rheumatoid Arthritis Systemic Lupus Erythematosus Multiple Sclerosis Autoimmune Hemolytic Anemia Myasthenia Gravis Pemphigus Vulgaris Celiac Disease Acute Infectious Mononucleosis Hemolytic Disease of the Newborn Toxic Shock Syndrome Lepromatous Leprosy Allergic Asthma
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